Buy SS-31 50mg Australia

Description

SS-31 (Elamipretide/MTP-131) is a cardiolipin-targeting tetrapeptide that accumulates selectively on the inner mitochondrial membrane, where it stabilises cristae architecture, reduces electron leakage, and enhances ATP production. Its amphipathic structure (alternating aromatic and cationic residues) confers high cell permeability and selective mitochondrial targeting. In aged cardiac models, 8-week SS-31 treatment has been reported to reverse age-related diastolic dysfunction and normalise mitochondrial proton leak (eLife, 2020). PNAS cross-linking/mass spectrometry studies have identified SS-31 protein interactors within the oxidative phosphorylation and 2-oxoglutarate metabolic pathways. This high-dose 50mg vial is suited for extended longitudinal animal studies, multi-arm dosing experiments, or research programmes requiring larger batch quantities of standardised material. Sequence: D-Arg-Dmt-Lys-Phe-NH2. CAS: 736992-21-5. For research use only. Not for human consumption.